Cloning and Molecular Characterization of the cDNA Encoding Histone H1 From Leishmania braziliensis

E. Martínez; M. C. Thomas; V. Alonso; E. Carmelo; A. C. González; A. Del Castillo; B. Valladares

doi:10.1645/0022-3395(2002)088[0199:CAMCOT]2.0.CO;2

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E. Martínez,¹ M. C. Thomas,² V. Alonso,¹ E. Carmelo,¹ A. C. González,¹ A. Del Castillo,¹ B. Valladares¹

¹Departamento de Parasitología, Ecología y Genética, Facultad de Farmacia, Universidad de La Laguna. c/ Astrofísico Francisco Sánchez, s/n., Tenerife 38271, Spain.
²Unidad Mixta de Investigaciones Médicas. Hospital Clínico Universitario San Cecilio, Dr. Oloriz, 16, 18012- Granada, Spain. Corresponding author. bvallada@ull.es

Abstract

The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out. The gene is present in the genome as a single copy and transcribed as a polyadenylated transcript of 830 nucleotides. The deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.

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E. Martínez, M. C. Thomas, V. Alonso, E. Carmelo, A. C. González, A. Del Castillo, and B. Valladares "Cloning and Molecular Characterization of the cDNA Encoding Histone H1 From Leishmania braziliensis," Journal of Parasitology 88(1), 199-203, (1 February 2002). https://doi.org/10.1645/0022-3395(2002)088[0199:CAMCOT]2.0.CO;2

Published: 1 February 2002

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